Tetrahexyldecyl ascorbate

Tetrahexyldecyl Ascorbate is a very stable, oil-soluble Vitamin C ester which has anti-oxidant activity, inhibiting lipid peroxidation. Topical use can mitigate the damaging effects of UV exposure. Studies have shown it to stimulate collagen production as well as clarifying and brightening the skin by inhibiting melanogenesis (the production of pigment) thereby promoting a more even skin tone. Unlike ascorbic acid, it will not exfoliate or irritate the skin.

Tetrahexyldecyl ascorbate (THDA) is a highly stable form of vitamin C that is considered an analogue of L-ascorbic acid. Enzymes within skin convert this form of vitamin C to pure vitamin C, ascorbic acid.

Unlike pure vitamin C (ascorbic acid), tetrahexyldecyl ascorbate is a lipid (fat) soluble. As such, it can penetrate further into the skin where it works with vitamin E (tocopherol) that’s naturally in your skin or in skincare products to target the skin’s underlying support system via a different pathway than water-soluble ascorbic acid.

Some researchers theorize that tetrahexyldecyl ascorbate has a greater affinity for skin because its fatty acid component helps aid penetration. It pairs well with other forms of vitamin C, vitamin E, green tea, and retinol for enhanced effectiveness and anti-aging benefits.

Its oil-soluble nature lets it neutralize the types of free radicals that damage skin lipids such as ceramides and cholesterol. This is primarily how it works as an antioxidant, while the water-soluble ascorbic acid helps neutralize other types of free radicals before they get too far past the skin’s surface.

Concentration-wise, amounts of 0.1% have antioxidant benefits, and it is often used at this level and up to 2% for maintaining skin health plus visibly soothing environmentally distressed skin.

If the goal is targeting hyperpigmentation, research shows amounts of 5% or greater are necessary for best results. It’s most effective when formulated at a pH of 6 or below and may be used with other discoloration-reducing ingredients such as niacinamide and licorice root where it’s been shown to deliver synergistic results. In fact, a 30% concentration of THD used with other discoloration-reducing ingredients was shown to improve stubborn hyperpigmentation and was even suitable for melasma-prone skin.

Tetrahexyldecyl ascorbate has a slightly oily feel and maybe colorless to pale yellow in appearance, depending on the supplier. It can be used in water-based formulas but must be combined with silicones or oils for ideal bioavailability.

Despite inherent stability, it’s not impervious to eventual degradation from ongoing exposure to light and strong sources of heat (above 113 degrees Fahrenheit/45 degrees Celsius). For this reason, we advise avoiding products with this ingredient packaged in jars or transparent materials.

Tetrahexyldecyl ascorbate is considered safe as used in cosmetics in concentrations up to 30% even when used with retinol, a 10% concentration of ascorbic acid, and other bio-active ingredients.

Additional information

Product Name

Tetrahexyldecyl Ascorbate/THDA



Molecular Formula



Tetrahexyldecyl ascorbate, Vitamin C


White Powder/Light yellow liquid

Grade Standard

Cosmetic Grade


-Special raw materials-/Purity ≧99%


CHA, Cosmetic additives, Preservatives


Available For Your Reference

Shipping Details

Customized, FOB, CIF, D2D

Additional Service

Supply, ODM/OEM, Wholesale


Please store it in a cool.

7 + 2 =


Green Stone Swiss Co ., Ltd.

Green Stone Swiss Co ., Limited has always focused on the supply of beauty, nutritional, and healthy ingredients. We mainly devote to the sale popularizing and research and services of natural products and promote the development of the natural herbal industry.


Xiamen, Shanghai; China

Business Type

Manufacturer, Marketing

Industry Experience

Over 20 Years

Main Markets
  • North America 51.00%
  • Western Europe: 10.00%
  • Northern Europe: 10.00%
Business Advantage

Support Formula Customization/ODM/OEM

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