Ligusticum Chuanxiong Extract Manufacturer & Supplier For Over 25 Years.

Active ingredients

Both kinds of chuanxiong contain volatile oil, and both are mainly composed of palmitic acid, angina lactone A, β-sitosterol, pregnanone, carotene, ferulic acid, protocatechuic acid, and caffeic acid, but the content of each is different. no change. Chuanxiong also contains alkaloids, such as ligustrazine, rye alkaloid, isoleucyl valine anhydride, etc.

Extraction processing method

Chuanxiong containing volatile oil can be prepared by steam distillation. Chuanxiong extract can be extracted with water, alcohol, etc. as a solvent, heated, and refluxed according to a conventional method, and then the extract is concentrated to dryness. Such as boiled chuanxiong, the extraction yield is above 30%.

Pharmacology

The two kinds of Chuanxiong essential oils have basically the same ability to eliminate DPPH free radicals; Ligustrazine in Chuanxiong extract has an antioxidant effect, can inhibit the generation of free radicals, and effectively scavenge oxygen free radicals. Ligustrazine can effectively inhibit the activity of melanocytes and reduce the production of melanin at low concentrations (50-400μg/mL), but high concentrations (>500μg/mL) show its cytotoxic effect. In a constant temperature and humidity chamber (30℃, RH32%), the hygroscopicity of the water extract of Japanese chuanxiong under low humidity was determined by the weighing method. After 6h, the weight of the chuanxiong extract sample increased by 78%. The water content of the stratum corneum can be measured by the conductometric method, and the conductance increased by 4.2 times compared with the blank test after the 50% alcohol extract of Japanese Chuanxiong was applied to the skin for one week.

• Promotion of glutathione reductase activity;
• Promotion of cathepsin activity;
• The proliferation of keratinocytes;
• Elimination of superoxide radicals;
• Promotion of luciferase activity;
• Activation of peroxidase-activated receptor (PPAR);
• The promotion of lipase activity by Chuanxiong extract;

Application in cosmetics&skin care products

Ligusticum Chuanxiong Extract can be used as a revitalizing anti-aging agent, antioxidant, skin lightening agent, moisturizing agent, anti-inflammatory agent, and slimming agent.