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The hair follicle is the basic unit of the hair, and the hair is formed by the growth and differentiation of the cells in the hair follicle. A group of hair follicle stem cells live in each hair follicle, supplying new cells to the growing hair follicle. Hair follicle stem cells are usually in a dormant state, but will rapidly activate and divide in a new round of hair growth cycle. Human hair follicle stem cells are a kind of adult stem cells and have the commonality of adult stem cells.

The size of the hair follicle is determined by the size of the dermal papilla and extracellular matrix. A healthy dermal papilla produces extracellular matrix proteins such as collagen III and fixing fibers such as laminin, collagen VII to make the hair root strong. Acetyl Tetrapeptide-3 is product obtained by the acetylation of Tetrapeptide-3. Acetyl tetrapeptide-3 is a 4 amino acids biomimetic peptide derived from a signal peptide which stimulate tissue remodeling by inducing collagen III.

If extracellular matrix renewal goes wrong, hair can become brittle. If this cycle continues, the hair follicles will eventually shrink. Acetyl Tetrapeptide-3 is a beauty peptide containing four amino acids. This peptide can quickly repair hair follicle cells, stimulate the natural growth of eyebrows, effectively reduce hair loss caused by aging, and make eyebrows thicker, natural, smoother and firmer.