Hesperetin is a plant chemical that is classified as a “bioflavonoid.” It is found primarily in citrus fruits. People use it as medicine.
Hesperetin alone, or in combination with other citrus bioflavonoids (diosmin, for example), is most often used for blood vessel conditions such as hemorrhoids,varicose veins, and poor circulation (venous stasis). It is also used to treatlymphedema, a condition involving fluid retention that can be a complication of breast cancer surgery.
Some research suggests that taking a specific product (Daflon 500, Les Laboratoires Servier) containing Hesperetin diosmin by mouth for up to 3 months improves symptoms of anal hemorrhoids. It may also preventhemorrhoids from coming back after they have healed.