Health benefits of Ellagic acid
Ellagic acid is a accustomed phenol antioxidant begin in abundant fruits and vegetables including blackberries, raspberries, strawberries, cranberries, walnuts, pecans, pomegranates, wolfberry and added bulb foods. The antiproliferative and antioxidant backdrop of ellagic acid accept spurred basic analysis into the abeyant bloom allowances of ellagic acerbic consumption.
Ellagic acid is the dilactone of hexahydroxydiphenic acid.
Ellagic acid was aboriginal analysis fabricated by chemist Michel Eugène Chevreul in oak galls and was added carefully advised by Henri Braconnot in 1831. Nierenstein able this actuality from algarobilla and assertive added fruits. Löwe was the aboriginal being to amalgamate ellagic acid by heating gallic acerbic with arsenic acid.
Plants aftermath ellagic acerbic and catechumen it to a anatomy of tannin accepted as ellagitannins. These are glucosides which are readily anatomize by baptize to change ellagic acerbic if the plants are eaten. The accomplished levels of ellagic acerbic are begin in strawberries, raspberries, cranberries, and grapes. It is aswell begin in peach.Ellagic acerbic can be begin in the augment Phellinus linteus.
Ellagic acid has antiproliferative and antioxidant backdrop in a amount of in vitro and small-animal models. The antiproliferative backdrop of ellagic acerbic are due to its adeptness to anon arrest the DNA bounden of assertive carcinogens, including nitrosamines and polycyclic ambrosial hydrocarbons. As with added polyphenol antioxidants, ellagic acerbic has a chemoprotective aftereffect in cellular models by abbreviation oxidative stress. However, one abstraction begin it to be afraid with catechins, such as those begin in tea.
These backdrop accept generated absorption in abeyant animal bloom allowances from the burning of ellagic acid. However, actual little abstraction of these proposed allowances has been appear as of 2010. A baby randomized controlled balloon involving 19 patients with carotid avenue binding begin that amethyst juice, which is top in ellagic acid, appeared to abate claret burden and carotid avenue bank thickness. A 2005 controlled abstraction of 48 patients ability chemotherapy for prostate blight begin that ellagic acerbic supplementation bargain the amount of chemotherapy-associated neutropenia (though there were no cases of astringent neutropenia in either the ellagic acerbic or ascendancy group). Ellagic acid supplementation did not advance all-embracing or progression-free adaptation of patients with prostate blight in this trial.
Despite the actual basic accompaniment of affirmation acknowledging bloom allowances in humans, ellagic acerbic has been marketed as a comestible supplement with a ambit of claimed allowances adjoin cancer, affection disease, and added medical problems. Ellagic acerbic has been articular by the U.S. Food and Drug Administration as a "Fake Blight Cure Consumers Should Avoid". A amount of U.S.-based sellers of comestible supplements accept accustomed Warning Letters from the Food and Drug Administration for announcement ellagic acerbic with claims that breach the Federal Food, Drug, and Cosmetic Act.