Glycyrrhetinic Acid

Glycyrrhetinic Acid

Other names : Enoxolone,Glycyrrhetin,Uralenic acid,Glycyrrhetinate,Arthrodont
CAS # : 471-53-4
Molecular formula : C30H46O4
Molar mass : 470.68 g/mol
Characteristics and Application :
Glycyrrhetinic acid is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which was obtained from the herb liquorice. It is used in flavouring and it masks the bitter taste of drugs like aloe and quinine. It is effective in the treatment of peptic ulcer and also has expectorant (antitussive) properties.
Glycyrrhetinic acid has also been reported to possess anti-inflammatory properties. It is believed to inhibit the enzymes that metabolize the prostaglandins, PGE2a to their inactive metabolites. This increases the level of prostaglandins in the digestive system. These prostaglandins inhibit gastric secretion but stimulate pancreatic secretion and mucous secretion in the intestines. This may be the reason that glycyrrhetinic acid is said to relieve peptic ulcers.
Glycyrrhetinic Acid is an oleanolic acid from Glycyrrhiza. Glycyrrhetinic Acid has some antiallergic, antibacterial, and antiviral properties. Orally, glycyrrhetinic acid has been used for its aldosterone effects in electrolyte regulation. Topically, glycyrrhetinic acid is used for allergic or infectious inflammation of the skin.
Use :
Glycyrrhetinic acid has reported used in the following product types: facial moisturizer/treatment; anti-aging; around-eye cream; moisturizer; after shave; after sun product; sunscreen spf 15 and above; oral pain relief; lip balm; facial cleanser .

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