Other names : vitamin D3, activated 7-dehydrocholesterol
Molecular formula C27H44O
Molar mass 384.64 g/mol
Appearance White, needle-like crystals
Melting point 83–86 °C
Cholecalciferol is a vitamin D3. Cholecalciferol is the naturally occurring form of vitamin D. It is a prehormone that is synthesized naturally in the skin by ultraviolet B irradiation of 7-dehydrocholesterol. Cholecalciferol is real vitamin D. All other compounds are either metabolic products or chemical modifications.Vitamin D is important for the absorption of calcium from the stomach and for the functioning of calcium in the body.
A combination of cholecalciferol and alendronate was approved by FDA for the treatment and prevention of osteoporosis.
Cholecalciferol is vitamin D3 which is required for normal bone formation. It is converted to 25-hydroxyvitamin D3 in the liver and then further converted to 1,25-dihydroxyvitamin D3 (calcitriol) in the kidney. This conversion is stimulated by parathyroid hormone and hypophosphatemia. As a result, 1,25-dihydroxyvitamin D3 increases the absorption of calcium and phosphate in the intestines.
Cholecalciferol is used to treat or prevent many conditions caused by a lack of vitamin D, especially conditions of the skin or bones.
Cholecalciferol may also be used for other purposes not listed in this medication guide.
Side effects :
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop taking cholecalciferol and call your doctor at once if you have a serious side effect such as:
thinking problems, changes in behavior, feeling irritable;
urinating more than usual;
chest pain, feeling short of breath; or
early signs of vitamin D overdose (weakness, metallic taste in your mouth, weight loss, muscle or bone pain, constipation, nausea, and vomiting).
This is not a complete list of side effects
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.
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