Cas # : 501-30-4
Other names : Kojic acid, 5-Hydroxy-2-(hydroxymethyl)-4-pyrone, 2-Hydroxymethyl-5-hydroxy-γ-pyrone
Molecular formula C6H6O4
Molar mass 142.11 g/mol
Appearance Tan powder
Melting point 152 - 155 °C
Solubility in water Soluble
Dissolving water, alcohol, acetone, slightly dissolving ether second ester of second acid, chloroform and pyridine, non-dissolving benzene
Characteristics and Application :
Kojic acid is a chelation agent produced by several species of fungi, especially Aspergillus oryzae, which has the Japanese common name koji. Kojic acid is a by-product in the fermentation process of malting rice, for use in the manufacturing of sake, the Japanese rice wine.
It is a mild inhibitor of the formation of pigment in plant and animal tissues, and is used in food and cosmetics to preserve or change colors of substances. It is used on cut fruits to prevent oxidative browning, in seafood to preserve pink and red colors, and in cosmetics to lighten skin. Kojic acid also has antibacterial and antifungal properties.It is also used in skin diseases like
It has been successfully used to lighten pigment spots and skin discoloration and considered as a kind of popularly specialized inhibitor for melanin. At present, it is assigned into various kinds of cosmetics for curing freckles, spots on the skin of elder men, pigmentation and acne.
Inhibit the melanin :
On a molecular level, melanin is produced in the body from the conversion (in several steps) of the amino acid tyrosine. The conversion requires the enzyme known as tyrosinase. Kojic acid can prevent the tyrosinase activity through synthesizing reaction with its antioxidant properties after penetrating upper skin layers and entering skin cells to inhibit the formation of pigment at the deep cells on the skin.
Kojic acid can produce excellent effects in even toning the skin, fighting age spots, pregnancy marks, freckles as well as general skin pigmentation disorders of face and body.
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